Wiskott-Aldrich syndrome (role of WASP).
نویسنده
چکیده
Wiskott-Aldrich syndrome (WAS) is an X-linked disorder characterized by thrombocytopenia, eczema and immunodeficiency. WASP, the gene responsible for WAS, has been identified by positional cloning, contains a PH domain, a GBD domain, a proline rich region, and a verprolin/cofilin homology domain. Subsequent studies suggest that WASP is involved in signal transduction and in the regulation of the cytoskeleton.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of medical and dental sciences
دوره 48 1 شماره
صفحات -
تاریخ انتشار 2001